Pseudomonas aeruginosa is a virulent bacteria, because of it's secreted toxic components, substances that have the ability to destroy tissues and blood cells. The good news is that the bacterium is an opportunist, that means that it causes infections only under certain conditions: e.g. in the context of other infections, when the body is already weak, in infants with congenital anomalies, dystrophic children, people with cystic fibrosis who are more susceptible to infections, etc.. So, in conclusion, it infects people who have a weak immune defense.
The bacterium is so dangerous because it is resistant to many antibiotics: e.g. penicillin and others. It has high resistance to antibiotics because it contains in it's structure, more accurate in it's the membrane, some proteins that eliminate antibiotics to the outside as they entered inside the bacteria, before they manage to destroy it. This is a natural antibiotic resistance but the resistance could be also acquired, because of the unjustified use of antibiotics.
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