If by better suited you mean faster speed and higher success rate of genetic transformation, then it's the organism composed of a single cell that is better suited. New gene only needs to be inserted into one cell in the organism, and when the organism reproduces the DNA gets copied (because single-celled organisms usually use asexual reproduction) the new genetic material is reproduced. It takes longer for the multicellular organisms to have a total genetic transformation.
I don't know how to properly explain it but it's pretty much self-explanatory...
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